Women's Health Weekly
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Breast Cancer
Ki67 breast cancer marker correlates with regulation of apoptosis-related genes
May 5th, 2005
The Ki67 breast cancer marker correlates with the regulation of apoptosis-related genes. According to a study from Singapore, "Ki67 is a nuclear protein that is tightly linked to the cell cycle. It is a marker of cell proliferation and has been used to stratify good and poor prognostic categories in invasive breast cancer. Its correlation with gene expression patterns has not been fully elucidated." "In this study," said researchers, "Ki67 immunohistochemistry using the MIB-1 antibody was performed on sections cut from 21 formalin-fixed, paraffin-embedded invasive breast cancers. Scoring was determined as nil (no immunostaining), low (10% or less...
Source: Women's Health Weekly (2005-05-05)
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