Women's Health Weekly
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Breast Cancer
Real-time PCR measures Epstein-Barr virus DNA in archival breast adenocarcinomas
May 5th, 2005
A real-time PCR assay measures Epstein-Barr virus DNA from archival breast adenocarcinomas. "The role of Epstein-Barr Virus (EBV) in breast cancer pathogenesis remains controversial. Fifty-five cases of paraffin-embedded, formalin-fixed invasive breast cancer were screened for the presence of EBV using quantitative polymerase chain reaction (PCR) directed at five different targets within the EBV genome (BamH1W, LMP1, EBNA1, LMP2, and BZLF1 regions). "In four tumors (7%), low level EBV DNA was detected by at least one of the assays, with levels of up to 11 copies of EBV DNA per 100,000 cells," scientists in the United States report. ...
Source: Women's Health Weekly (2005-05-05)
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