Women's Health Weekly
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Breast Cancer
Tenascin-W implicated as breast cancer diagnostic marker
May 5th, 2005
Tenascin-W has been implicated as a breast cancer diagnostic marker. According to recent research from Switzerland, "Tenascins represent a family of extracellular matrix glycoproteins with distinctive expression patterns. Here we have analyzed the most recently described member, tenascin-W, in breast cancer. Mammary tumors isolated from transgenic mice expressing hormone-induced oncogenes reveal tenascin-W in the stroma around lesions with a high likelihood of metastasis." "The presence of tenascin-W was correlated with the expression of its putative receptor, alpha8 integrin. HC11 cells derived from normal mammary epithelium do not express alpha8...
Source: Women's Health Weekly (2005-05-05)
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