Angiology

Rat study suggests reduced uteroplacental perfusion pressure leads to IUGR

Published in Women's Health Weekly, May 12th, 2005

According to a study from the United States, "Evidence continues to implicate reduced placental perfusion as the cause of preeclampsia, initiating a sequence of events leading to altered vascular function and hypertension.

"The present study was designed to determine the influence of reduced uteroplacental perfusion pressure (RUPP) on the responsiveness of uterine arcuate resistance arteries."

C.M. Anderson and colleagues, University of North Dakota, wrote, "A condition of RUPP was surgically induced in pregnant Sprague-Dawley rats on Gestational Day 14. On Gestational Day 20, uterine arcuate arteries were mounted on a small-vessel wire myograph and...

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Source: Women's Health Weekly (2005-05-12)

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