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Women's Health Weekly

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Breast Cancer



Recent studies add new data to breast cancer research



May 12th, 2005

Investigators in the United States have published new breast cancer data.

Study 1: The presence of a polymorphism in the cyclin D1 gene appears to reduce the effect of hormonal exposure on postmenopausal breast cancer, and predicts survival, according to a study from Vanderbilt University.

"Cyclin D1 (CCND1) is a key cell cycle regulatory protein that governs cell cycle progression from the G(1) to S phase. A common polymorphism (A870G) in exon 4 of the CCND1 gene produces an alternate transcript (transcript-b) that preferentially encodes a protein with enhanced cell transformation activity and possible prolonged half-life," explained Xiao-Ou Shu and...


Source: Women's Health Weekly (2005-05-12)

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