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Women's Health Weekly

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Breast Cancer



Baseline spinal BMD may predict risk of chemotherapy-induced ovarian failure



May 12th, 2005

Baseline spinal bone mineral density may predict risk of chemotherapy-induced ovarian failure in breast cancer patients, Ohio State University researchers say.

"Age at treatment and the total cumulative dose of cyclophosphamide are established predictors of chemotherapy-induced ovarian failure in premenopausal women with breast cancer. In a prospective trial of 49 women receiving adjuvant chemotherapy, we sought to identify whether other factors including family history of osteoporosis, lifestyle factors, reproductive hormones, bone turnover markers, or bone mineral density (BMD) of the hip or total spine measured before (baseline) and 6 months after chemotherapy...


Source: Women's Health Weekly (2005-05-12)

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