Women's Health Weekly
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Breast Cancer
ERbeta, hormone receptors, biomarker associations in breast cancer evaluated
May 12th, 2005
Associations between estrogen receptor beta, hormonal receptors, and other prognostic biomarkers were evaluated in breast cancer. "The estrogen receptor (ER)-beta isoform has been recently identified to be distinct from ERalpha isoform and regulates separate sets of genes, and can exert opposite signaling functions depending on the ligand and response elements," scientists in the United States report. "Previous studies of ERbeta have been at the mRNA level and few by immunohistochemistry, and the results are inconsistent. In this study the authors compared expression of ERbeta with those of other prognostic biomarkers by immunohistochemistry on...
Source: Women's Health Weekly (2005-05-12)
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