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Women's Health Weekly

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Breast Cancer



Gene expression profiling identifies molecular subtypes of inflammatory disease



May 12th, 2005

According to a study from France, "Breast cancer is a heterogeneous disease. Comprehensive gene expression profiles obtained using DNA microarrays have revealed previously indistinguishable subtypes of noninflammatory breast cancer (NIBC) related to different features of mammary epithelial biology and significantly associated with survival."

"Inflammatory breast cancer (IBC) is a rare, particular, and aggressive form of disease," wrote F. Bertucci and colleagues, INSERM, UMR599, Marseille. "Here we have investigated whether the five molecular subtypes described for NIBC (luminal A and B, basal, ERBB2 overexpressing, and normal breast-like) were also present in...


Source: Women's Health Weekly (2005-05-12)

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