Women's Health Weekly
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Breast Cancer
Higher allelic imbalance rates seen in primary than metastatic tumors
May 12th, 2005
Higher allelic imbalance rates occur in primary breast tumors than metastatic tumors, researchers have found. They say this suggests that a tumor's metastatic potential may be determined early in carcinogenesis. "Axillary lymph node status is the most important prognostic factor in predicting disease outcome in women with breast cancer. A number of chromosomal aberrations in primary breast tumors have been correlated with lymph node status and clinical outcome, but chromosomal changes particular to metastatic lymph node tumors have not been well studied," said R.E. Ellsworth and colleagues, Windber Research Institute, Windber, Pennsylvania. ...
Source: Women's Health Weekly (2005-05-12)
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