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Adverse Drug Reaction

Aromatase inhibitors' possible neurodegenerative effects need study

Published in Women's Health Weekly, May 12th, 2005

According to a recent article in Geburtshilfe und Frauenheilkunde, "Impressive successes have been achieved with the possibilities offered by the endocrinal treatment of metastasizing breast cancer.

"Adjuvant endocrinal therapy is presently undergoing a change. Should we continue to prescribe tamoxifen as we have been doing for the past 30 years, or should we resort to administering aromatase inhibitors for up to 5 or more years' Before initiating a large-scale change we should make every effort to find out whether there would be any long-term adverse effects on the central nervous system," wrote J.M. Wenderlein and colleagues, University of Ulm.

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