Women's Health Weekly
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Breast Cancer
LOH in ductal lavage compared in breasts with and without tumors
May 19th, 2005
According to a study from Japan, "Detection of breast cancer at an early stage is the key to successful treatment and outcome. In tumors confined to the breast at diagnosis, stage is the most important prognostic factor. If detected early, breast cancer is eminently curable." "We measured loss of heterozygosity (LOH) using 9 microsatellite markers in epithelial cells obtained by ductal lavage (DL) from 59 women before breast surgery (excisional biopsies, duct resections, and mastectomies). In addition, we analyzed LOH obtained by DL in the contralateral breast of breast cancer patients," reported Y. Yonekura and colleagues, Kansai Medical University, Osaka. ...
Source: Women's Health Weekly (2005-05-19)
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