Diagnostics

Rapid QF-PCR prenatal test of aneuploidy validated

Published in Women's Health Weekly, May 19th, 2005

According to a paper in the Journal of Histochemistry & Cytochemistry, "Molecular cytogenetic aneuploidy testing for pregnant women at increased risk of chromosome abnormality leads to rapid reassurance for those with normal results and earlier decisions on pregnancy management in the case of abnormality."

C.M. Ogilvie and colleagues at Guy's & St Thomas' Hospital Trust, London, "tested 9,080 prenatal samples using a one-tube QF-PCR [quantitative fluorescence-polymerase chain reaction] test for trisomies 13, 18, and 21."

Results showed an abnormality rate of 5.9%.

"There were no misdiagnoses for nonmosaic trisomy," the...

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Source: Women's Health Weekly (2005-05-19)

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