Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Hormone decreases cancer cells' ability of to spread, animal study shows
May 26th, 2005
A hormone used in the contraceptive Depo-Provera increased expression of a metastasis suppressor gene and decreased the ability of breast cancer cells to spread in both laboratory experiments and an animal model. Medroxyprogesterone acetate (MPA) is a progestin used in Depo-Provera; it has been tested as a treatment for advanced breast cancer. An earlier study found that MPA increases the expression of a metastasis suppressor gene called Nm23-H1 in estrogen and progesterone receptor-negative breast cancer cells via the glucocorticoid receptor. Patricia S. Steeg, PhD, of the U.S. National Cancer Institute, and colleagues tested whether treating...
Source: Women's Health Weekly (2005-05-26)
|
