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Women's Health Weekly

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Chronic Fatigue Syndrome



Disturbance of HPA axis in CFS characterized by underactivation of HPA axis



May 26th, 2005

According to recent research published in the journal Endocrinologist, "Chronic fatigue syndrome (CFS) is a disease characterized by debilitating fatigue of at least 6 months' duration. The pathophysiology and the localization of the underlying hypothalamopituitary-adrenal (HPA) axis disturbance are a matter of debate."

H.B. Izgi and colleagues, Erciyes University, Kayseri, Turkey, "[evaluated] the HPA axis by the 1 mcg adrenocorticotrophic hormone (ACTH) test and metyrapone test in patients with CFS and [compared] the size of the adrenal glands of the patients with that of the control subjects."

According to their paper, "Twenty patients (14...


Source: Women's Health Weekly (2005-05-26)

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