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Women's Health Weekly

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Assisted Reproduction



Superovulation may increase risk of imprinting defects



May 26th, 2005

Superovulation may increase risk of imprinting defects, endocrinologists say.

Study results also suggest that imprinting defects and subfertility may have a common etiology.

"Recent case reports have suggested that infertility treatment with intracytoplasmic sperm injection (ICSI) may increase the risk of imprinting defects leading to Angelman syndrome (AS)," noted M. Ludwig and colleagues, Endokrinologikum Hamburg. "Although imprinting defects account for only 4% of patients with AS, we have found four cases among 16 AS patients born to subfertile couples, who conceived with or without infertility treatment (25%; relative risk (RR) 6.25; 95%...


Source: Women's Health Weekly (2005-05-26)

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