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Women's Health Weekly

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Breast Cancer



Mammaglobin A is a promising marker for breast cancer



June 2nd, 2005

Mammaglobin A is a promising marker for breast cancer.

"Existing serum-based markers for breast cancer all lack organ specificity. Mammaglobin A (MGA) is a 93 amino acid protein expressed almost exclusively in breast tissue. The aim of our study was to investigate the different forms of MGA protein in fibroadenomas and breast carcinomas," scientists in Ireland report.

"MGA protein was measured by Western blotting in 132 breast cancers, 29 fibroadenomas and 14 nonbreast tissues. MGA protein in breast tissue was found to exist in 2 main forms. These forms migrated with approximate molecular masses of 18 and 25 kDa.

"Both forms of...


Source: Women's Health Weekly (2005-06-02)

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