Women's Health Weekly
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Breast Cancer
RAD21 supression decreases cell growth in breast cancer cells
June 2nd, 2005
RAD21 suppression decreases cell growth in breast cancer cells. According to recent research from the United States, "A genome-wide case-control association study done in our laboratory has identified a single nucleotide polymorphism located in RAD21 as being significantly associated with breast cancer susceptibility. "RAD21 is believed to function in sister chromatid alignment as part of the cohesin complex and also in double-strand break (DSB) repair. Following our initial finding, expression studies revealed a 1.25- to 2.5-fold increased expression of this gene in several human breast cancer cell lines as compared with normal breast...
Source: Women's Health Weekly (2005-06-02)
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