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Women's Health Weekly

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Acute Liver Failure



HLA homozygosity confers susceptibility to non-A non-B hepatitis



June 2nd, 2005

HLA homozygosity confers susceptibility to non-A non-B hepatitis.

"For the majority of cases of acute liver failure in western Europe and North America an etiology cannot be defined. The condition is most often called fulminant non-A, non-B (NANB) hepatitis. Features such as female preponderance and presence of serum autoantibodies suggest a possible autoimmune basis. The aim of the present paper was to examine a possible human leukocyte antigen (HLA) association with fulminant NANB hepatitis," scientists in Australia report.

"HLA A, B, and DR data of 55 adult Caucasian fulminant NANB patients were compared with those of 1449 local Caucasian...


Source: Women's Health Weekly (2005-06-02)

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