Women's Health Weekly
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Atherosclerosis
Tibolone associated with upregulated expression of estrogen and LDL receptors
June 9th, 2005
The menopausal drug tibolone is associated with upregulated expression of estrogen and low density lipoprotein (LDL) receptors, whereas simvastatin isn't, shows an analysis of a study conducted in rabbits. "After menopause women are more susceptible to coronary heart disease due to increased risk of atherosclerosis. Tibolone (Livial) is an innovative synthetic steroid analogue for the treatment of postmenopausal climacteric symptoms including atherosclerosis, but the mechanisms of its effect are still unclear," said Y.L. Cui and colleagues, China Agriculture University, Beijing. They compared "the [effects] of tibolone and simvastatin on...
Source: Women's Health Weekly (2005-06-09)
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