Women's Health Weekly
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Menopause
Single-dose MPA reduces hot flashes more than daily venlafaxine
June 9th, 2005
Analysis of clinical trial data shows a single dose of the progestational agent medroxyprogesterone acetate (MPA) alleviated hot flashes more than did the daily use of the oral antidepressant venlafaxine (Effexor). Three to 4 weeks after treatment began, researchers observed that MPA was more effective than venlafaxine. This difference became even more striking after 6 weeks of treatment, said Mayo medical oncologist Charles Loprinzi, MD, the study's lead investigator. "This improved hot-flash benefit appeared to last for at least 6 months following a single MPA dose, with almost three times as many patients still reporting a 90% hot-flash reduction...
Source: Women's Health Weekly (2005-06-09)
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