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Women's Health Weekly

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Antioxidants



Efficacy of tamoxifen augmented rat breast tumorigenesis



June 23rd, 2005

Efficacy of tamoxifen augmented in rat breast tumorigenesis.

According to a study from India, "Reactive oxygen species (ROS) play a major role in causing mitochondrial changes linked to cancer and metastasis. Uptake of antioxidants by tissue to reduce the ROS production could be instrumental in controlling cancer."

"Tamoxifen (TAM), a nonsteroidal anti-estrogen drug, [is] most used in the chemotherapy and chemoprevention of breast cancer," explained S.S. Perumal and colleagues, University of Madras. "Riboflavin, niacin and coenzyme Q10 (CoQ10 ) are proved to be potent antioxidants and protective agents against many diseases...


Source: Women's Health Weekly (2005-06-23)

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