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Polycystic Ovary Syndrome

Proteomic approach may help classify patients by PCOS etiology

Published in Women's Health Weekly, June 23rd, 2005

Investigators in Finland conducted a study of "gene expression profiles of connective tissue components in polycystic ovaries using complementary deoxyribonucleic acid (cDNA) array technology."

Their study subjects were "eight women with polycystic ovary syndrome (PCOS) and two normally cycling women treated with electrocauterization and hysterectomy, respectively."

They measured "expression levels of 588 genes involved in cellular invasion, extracellular matrix (ECM) turnover, and cell-ECM interactions in" DNA collected from polycystic ovary biopsy samples.

S. Oksjoki and colleagues at the University of Turku and the Family...

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