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Women's Health Weekly

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Breast Cancer



More protection from early breast cancer recurring with letrozole, study shows



June 23rd, 2005

Initial treatment with letrozole offers significantly greater post-surgery protection against breast cancer recurrence than does tamoxifen in postmenopausal women with early breast cancer (19% less risk of recurrence, p=0.003), according to newly updated results of the Breast International Group 1-98 trial.

In addition, the data showed letrozole reduced the risk of cancer spreading to other parts of the body (distant metastases) by 27% (p=0.0012).

"In our study, letrozole out-performed tamoxifen in a number of critical endpoints, among them reducing both the risk of recurrence and the risk of distant metastases in postmenopausal women with hormone...


Source: Women's Health Weekly (2005-06-23)

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