Women's Health Weekly
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Breast Cancer
Synaptotagmin implicated in human breast cancer
June 23rd, 2005
Scientists implicated synaptotagmin in human breast cancer. In a recent study, researchers in India conducted a study "to analyze the pattern of changes in GSTs in cancerous and adjacent noncancerous tissues obtained from breast cancer patients undergoing surgery. Cytosolic GST purification, assay of GST, protein expression levels, and GST-synaptotagmin association were analyzed using standard biochemical techniques like GSH-affinity purification, spectrophotometry, SDS-PAGE, Western blots, and matrix-assisted laser desorption and ionization-time of flight (MALDI-TOF)." "GST activity in cancerous tissues (.26 U/mg protein) was significantly higher...
Source: Women's Health Weekly (2005-06-23)
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