Drug Resistance

New polysaccharide may help combat multidrug resistance in cancer

Published in Women's Health Weekly, June 23rd, 2005

In a recent study, scientists report that a molecule previously thought to play a purely structural and inert role in cells is actually involved in multidrug resistance in cancer. Using antagonists for this molecule, the researchers were able to sensitize drug-resistant breast cancer cells to chemotherapeutic drug treatment.

The research appeared in the Journal of Biological Chemistry.

Multidrug resistance is very common in most types of cancers, making it one of the leading problems in cancer therapy. It is often caused by an increase in the cell's production of proteins that transport drugs out of the cell, preventing the drugs from...

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Source: Women's Health Weekly (2005-06-23)

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