Women's Health Weekly
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Breast Cancer
Studies add new findings to breast cancer body of knowledge
June 30th, 2005
New findings from the United States describe advances in breast cancer. Study 1: According to a paper in a recent issue of Molecular Endocrinology, "Progesterone receptors (PRs) are prognostic markers in breast cancers irrespective of the patient's progestational status. However, there are two PR isoforms, PR-A and PR-B that are equimolar in the normal breast but dysregulated in advanced disease. "Postmenopausal, tamoxifen-treated patients with estrogen receptor (ER)-positive, PR-A-rich tumors have much faster disease recurrence than patients with PR-B-rich tumors." "To study the mechanisms we engineered ER+ breast cancer...
Source: Women's Health Weekly (2005-06-30)
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