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Women's Health Weekly

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Breast Cancer



Gene linked to lower disease risk



June 30th, 2005

Scientists at the Medical University Graz in Austria report that a specific genetic variation in a cytokine gene is associated with lower breast cancer risk.

Cytokines are molecules that act as signals between cells. Uwe Langsenlehner and colleagues were examining the cytokine interleukin (IL)-10, which is involved in the development of various tumors.

"In breast cancer risk, IL-10 may be a two-edged sword," Langsenlehner said. "On one hand, higher IL-10 levels could facilitate development of cancer by supporting tumor escape from the immune response. On the other hand, the antiangiogenic effects of IL-10 are supposed to prevent or reduce tumor...


Source: Women's Health Weekly (2005-06-30)

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