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Women's Health Weekly

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Breast Cancer



Recurrence correlates with genetic changes in normal-looking tissue near tumors



June 30th, 2005

By identifying telltale genetic changes in breast tissues that appear normal, a new test may help predict the return of breast cancer after treatment, report researchers at the University of New Mexico School of Medicine.

The assay measures the DNA content of telomeres (TC) - specialized nucleoprotein complexes that cap the ends of chromosomes, which are altered in tumors.

"We wanted to confirm that shortening of telomeres leads to genomic instability, which is a critical step in the progression to recurrent cancer," said Christopher Heaphy, a PhD student in the department of biochemistry and molecular biology, University of New Mexico School of...


Source: Women's Health Weekly (2005-06-30)

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