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Women's Health Weekly

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Breast Cancer



TAA-based DNA vaccines show promise against metastatic disease



June 30th, 2005

Tumor associated antigen-based DNA vaccines show promise against metastatic disease in breast cancer patients.

According to recent research published in the journal Breast Cancer Research and Treatment, "Anti-tumor vaccines are a relatively non-toxic alternative to conventional chemotherapeutic strategies to control breast cancer. Immunization with tumor-associated antigens (TAAs) triggers anti-tumor cytotoxic T lymphocytes (CTL), which can limit tumor progression."

R.K. Sypniewska and associates at the University of Texas explained, "Here we report on the development and effectiveness of a TAA-based DNA vaccine encoding Mage-b1/2, the mouse...


Source: Women's Health Weekly (2005-06-30)

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