Women's Health Weekly
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Breast Cancer
Tumor cells from human breast cancer detected and quantified in mouse models
June 30th, 2005
Tumor cells from human breast cancer were detected and quantified in mouse models by using immunomagnetic enrichment and multiparameter flow cytometry. According to a study from Canada, "Circulating tumor cells (CTCs) in the peripheral blood of breast cancer patients may be an important indicator of metastatic disease and poor prognosis. However, the use of experimental models is required to fully elucidate the functional consequences of CTCs." "The purpose of this study was to optimize the sensitivity of multiparameter flow cytometry for detection of human tumor cells in mouse models of breast cancer. MDA-MB-468 human breast cancer cells were...
Source: Women's Health Weekly (2005-06-30)
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