Women's Health Weekly
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Cancer Prevention
"Developmental reprogramming" could explain cancer risk
June 30th, 2005
M. D. Anderson Cancer Center may have uncovered the reason why some people who are genetically predisposed to hormone-dependent cancers develop the disease as an adult, while others who are similarly susceptible don't. In a study published on-line in the Proceedings of the National Academy of Sciences (PNAS), they show, for the first time, that exposure to a pharmaceutical estrogen during fetal development can permanently "reprogram" tissue in a way that determines whether tumors will develop in adulthood. While the study was conducted with rats that are susceptible to benign uterine tumors, and the compound used was diethylstilbestrol (DES),...
Source: Women's Health Weekly (2005-06-30)
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