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Women's Health Weekly

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Breast Cancer



Adjuvant docetaxel improves survival in women with node-positive disease



July 14th, 2005

Overall survival is improved among women with node-positive breast cancer who receive adjuvant docetaxel compared with those receiving fluorouracil, study results indicate.

"We compared docetaxel plus doxorubicin and cyclophosphamide (TAC) with fluorouracil plus doxorubicin and cyclophosphamide (FAC) as adjuvant chemotherapy for operable node-positive breast cancer. We randomly assigned 1,491 women with axillary node-positive breast cancer to 6 cycles of treatment with either TAC or FAC as adjuvant chemotherapy after surgery. The primary end point was disease-free survival," wrote M. Martin and colleagues, Hospital University of San Carlos, Madrid.

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Source: Women's Health Weekly (2005-07-14)

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