Women's Health Weekly
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Breast Cancer
E-cadherin expression in lymph node metastases predicts survival
July 21st, 2005
E-cadherin expression in lymph node metastases predicts survival in breast cancer patients. "The tumor suppressor adhesion molecule E-cadherin is believed to have an anti-invasive role in breast cancer," oncologists in the United States explained. "Lymph node involvement is the best prognostic marker known, yet there is variability in outcome among node-positive patients." In their study, M. Harigopal and coauthors at Yale University sought to clarify "the relationship between E-cadherin expression in primary invasive ductal tumors and corresponding nodal metastases," and to determine "the prognostic value of E-cadherin expression in node-positive...
Source: Women's Health Weekly (2005-07-21)
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