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Women's Health Weekly

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Breast Cancer



Optical imaging of breast tumors achieved via 'Smart' optical probes



July 21st, 2005

Optical imaging of spontaneous breast tumors was performed by using protease sensing 'smart' optical probes.

According to a study from Germany, "The objective of this study was to determine if spontaneous breast cancer lesions can be detected by fluorescence reflectance imaging (FRI) and fluorescence mediated tomography (FMT) using protease-sensing optical probes. Transgenic [FVB/N-TgN (WapHRAS)-69Lin y(SJL))] mice, which spontaneously develop breast cancer, were injected intravenously with a cathepsin-sensing fluorescent imaging probe."

"FRI and EMT were performed 24 hours after probe injection and region of interest (ROI) analysis was performed....


Source: Women's Health Weekly (2005-07-21)

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