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Endometrial Cancer

Phase II clinical trial of cell-signaling protein inhibitor seeks patients

Published in Women's Health Weekly, July 21st, 2005

Ariad Pharmaceuticals, Inc. (ARIA) announced initiation of enrollment of patients with recurrent or persistent endometrial cancer in a global Phase II clinical trial of its novel mTOR inhibitor, AP23573, as a single agent.

This nonrandomized study will evaluate the clinical benefit of AP23573 in well-characterized endometrial cancer patients. Up to approximately 45 patients will be enrolled in the trial at several centers in the United States and Europe. AP23573 will be administered intravenously using a daily dosing regimen. Patients will be followed for at least 6 months after enrollment but may continue on AP23573 if they have clinical benefit.

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