Women's Health Weekly
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Apoptosis
Role of ADAM12 in breast tumor progression and stromal cell apoptosis clarified
July 28th, 2005
The role of ADAM12 in breast tumor progression and stromal cell apoptosis was clarified. According to recent research published in the journal Cancer Research, "As in developmental and regenerative processes, cell survival is of fundamental importance in cancer. Thus, a tremendous effort has been devoted to dissecting the molecular mechanisms involved in understanding the resistance of tumor cells to programmed cell death." "Recently, the importance of stromal fibroblasts in tumor initiation and progression has been elucidated. Here, we show that stromal cell apoptosis occurs in human breast carcinoma but is only rarely seen in nonmalignant...
Source: Women's Health Weekly (2005-07-28)
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