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Women's Health Weekly

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Breast Cancer



Cancer patients with recurrence, metastasis present fewer apoptotic cells



July 28th, 2005

Apoptosis and production of TNF-alpha by tumor-associated inflammatory cells in histological grade III breast cancer was observed and reported by scientists in Brazil.

"Tumor necrosis factor alpha (TNF-alpha) is a cytokine that acts as an important mediator of the apoptotic process that also demonstrates selective cytotoxicity against malignant breast tumor cells," investigators in Brazil reported.

"In the present study, the presence of apoptotic tumor cells and the synthesis of TNF-alpha by inflammatory cells were investigated in tissue samples from grade III invasive breast cancer with long-term follow-up," wrote F.R. Estevam and colleagues,...


Source: Women's Health Weekly (2005-07-28)

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