Women's Health Weekly
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Breast Cancer
Phytoestrogens and 17 beta-estradiol inhibited apoptosis in breast cancer cells
July 28th, 2005
Phytoestrogens combined with 17 beta-estradiol to inhibit apoptosis in MCF-7 breast cancer cells. "Phytoestrogens have been described to be weak estrogens, SERMs or exhibit antiestrogenic properties. However, information about their activity in presence of estrogens is limited," scientists writing in the Journal of Steroid Biochemistry and Molecular Biology reported. "Therefore, we have analyzed the dose dependent combinatory activity of the phytoestrogens genistein (Gen), daidzein (Dai) and coumestrol (Cou), and 17 beta-estradiol (E2) on cell proliferation and apoptosis induction in human MCF-7 breast cancer cells. Neither additive nor...
Source: Women's Health Weekly (2005-07-28)
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