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Women's Health Weekly

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Anicemycin



Anicemycin inhibited anchorage-independent growth of tumor cells



July 28th, 2005

Anicemycin was suggested to inhibit anchorage-independent growth of tumor cells.

According to a study from Japan, "The anchorage-independence of cells is closely related to their tumorigenicity. In the screening of inhibitors of anchorage-independent growth of tumor cells, anicemycin was isolated from the fermentation broth of an actinomycete strain TP-A0648."

"The producing strain was isolated from a leaf of Aucuba japonica collected in Toyama, Japan and identified as Streptomyces sp. based on the taxonomic data. The structure of anicemycin was elucidated as a new analog of spicamycin by NMR and MS analysis," explained Y. Igarashi and...


Source: Women's Health Weekly (2005-07-28)

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