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Radionuclide

Radionuclide 177Lu showed promise as radiotherapeutic agent

Published in Women's Health Weekly, August 4th, 2005

The radionuclide 177Lu has shown promise as a radiotherapeutic agent.

"177Lu is presently being considered as one of the most promising radionuclide for targeted therapy owing to its suitable decay characteristics. 177Lu in high radionuclidic purity (99.99%) and moderate specific activity (100-110 TBq/g) was produced using enriched (60.6% 176Lu) Lu2O3 target. The macrocycle 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is known to form stable complexes with lanthanides," scientists in India reported.

"Herein, we describe a novel attempt to introduce 177Lu in the estradiol moiety through a steroidal-BFCA (Bifunctional Chelating...

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