Women's Health Weekly
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Cancer Vaccines
Studies advance knowledge in cancer vaccines research
August 4th, 2005
Cancer vaccines research advances have been reported from the United States and New Zealand. Study 1: A DNA vaccine targeting Fos-related antigen 1 enhanced by IL-18 induces long-lived T-cell memory against tumor recurrence. "A novel vaccination strategy induced specific CW8+ T cell-mediated immunity that eradicated spontaneous and experimental pulmonary cancer metastases in syngeneic mice and was also effective in a therapeutic setting of established breast cancer metastases. This was achieved by targeting transcription factor Fos-related antigen 1(Fra-1), overexpressed by many tumor cells, with an ubiquitinated DNA vaccine against Fra-1,...
Source: Women's Health Weekly (2005-08-04)
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