Women's Health Weekly
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Breast Cancer
Common ATM polymorphism associated with bilateral breast cancer
August 11th, 2005
Common ATM polymorphism associated with bilateral breast cancer. According to recent research published in the International Journal of Cancer, "The ATM kinase has an essential role in maintaining genomic integrity. Loss of both ATM alleles results in ataxia-telangiectasia (A-T), a rare autosomal recessive neuroimmunologic disorder associated with cancer susceptibility. Individuals heterozygous for germ-line ATM mutations have been reported to have an increased risk for malignancy, in particular, female breast cancer." "In the current study, a full mutation analysis of the ATM gene was carried out in patients from 121 breast or breast-ovarian...
Source: Women's Health Weekly (2005-08-11)
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