Women's Health Weekly
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Breast Cancer
Expression and prognostic value of activated ERK1/2 in breast cancer examined
August 11th, 2005
Scientists studied the expression and prognostic relevance of activated extracellular-regulated kinases (ERK1/ERK2) in breast cancer. According to a study from Germany, "ERK1/ERK2 play important roles in the malignant behavior of breast cancer cells in vitro. In our present study, 148 clinical breast cancer samples (120 cases with follow-up data) were studied for the expression of ERK1/ERK2 and their phosphorylated forms p-ERK1 and p-ERK2 by immunoblotting, and p-ERK1/2 expression in corresponding paraffin sections was analyzed by immunohistochemistry." "The results were correlated with established clinical and histological prognostic parameters,...
Source: Women's Health Weekly (2005-08-11)
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