Women's Health Weekly
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Breast Cancer
IFNG polymorphism in intron 1 associated with increased risk of breast cancer
August 11th, 2005
Functional interferon (IFN) polymorphism in intron 1 might be associated with an increased risk of developing sporadic breast cancer. According to recent research from India, "IFN-gamma is an important Th1 cytokine, which plays a role in immune surveillance and anti-tumor activity. A case-control study involving 54 sporadic breast cancer patients and 144 healthy controls was carried out to explore if the genotype variation of a proposed non-specific enhancer element with a dinucleotide (CA)n repeat in intron 1 has a role in the susceptibility to promote sporadic breast cancer." "Genotype analysis carried out by single-strand length...
Source: Women's Health Weekly (2005-08-11)
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