Women's Health Weekly
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Breast Cancer
Role of calcium/calmodulin-dependent kinase in cell proliferation clarified
August 11th, 2005
Scientists clarified the role of calcium/calmodulin-dependent kinase (CaM-K) in cell proliferation. According to recent research from the United States, "Calcium is universally required for cell growth and proliferation. Calmodulin is the main intracellular receptor for calcium." "Although calcium and calmodulin are well known to be required for cell cycle regulation, the target pathways for their action remain poorly defined. Potential targets include the CaM-K. The aim of this study was to determine the role of the CaM-Ks on cell proliferation and progress through the cell cycle in breast cancer cells. CaM-KI inhibition with either KN-93 or...
Source: Women's Health Weekly (2005-08-11)
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