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Women's Health Weekly

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Breast Cancer



Scientists link genotype to circulating estrogens and breast cancer risk



August 11th, 2005

Scientists link genotype to circulating estrogens and the risk of breast cancer.

"There is evidence that circulating estrogens are associated with breast cancer risk. In this study of premenopausal women, we explored the association of polymorphisms in genes in the estrogen synthesis and metabolism pathways with serum and urinary levels of estrone (E-1) and estradiol (E-2) and with the urinary ratio of 2-hydroxyestrone (2-OHE1)/16 alpha-hydroxyestrone (16 alpha-OHE1)," scientists in the United States report.

"This analysis included 220 women, who were participants in a 2-year randomized soy intervention," explained G. Lurie and colleagues at the...


Source: Women's Health Weekly (2005-08-11)

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