Women's Health Weekly
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Breast Cancer
RASSF1A mutation linked to heightened breast tumor risk
August 18th, 2005
An RASSF1A mutation has been linked to a heightened risk of breast tumor development. "The tumor suppressor gene RASSF1A is inactivated or mutated in different tumor entities including breast cancer;" however, the "frequency of the genomic variants of RASSF1A in patients with breast tumors has not been evaluated," oncologists in Germany explained. In their study, U. Schagdarsurengin and coauthors at the University of Halle-Wittenberg examined "the association between ten nucleotide polymorphisms of RASSF1A and the risk of breast cancer in 178 cases with tumorous alterations of mammary tissue (including 141 carcinomas and 37 fibroadenomas) and 70...
Source: Women's Health Weekly (2005-08-18)
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