Women's Health Weekly
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Genetics & Genomics
Genes are found to be upregulated in preeclampsia
August 18th, 2005
Genes are found to be upregulated in cases of severe early-onset preeclampsia. "Preeclampsia is an important clinical condition with unknown etiology. We used DNA array technique to compare placental gene expression profile in severe early-onset preeclampsia from 25 to 27 gestational weeks with strictly nonaffected placental samples from similar gestational weeks. DNA arrays were validated by showing the upregulation of several genes typical for preeclampsia such as chorionic gonadotrophin beta-chain, tissue factor pathway inhibitor, and intercellular adhesion molecule-1," researchers in Finland report. "In DNA array, 5% of genes displayed less than...
Source: Women's Health Weekly (2005-08-18)
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