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Women's Health Weekly

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Reproduction



Ovulatory follicle rupture studied, role of metalloproteinases clarified



August 18th, 2005

Recently published research from Japan has reported that gelatinase A and membrane-type matrix metalloproteinases (MMPs) 1 and 2 are responsible for follicle rupture during ovulation in the medaka.

"Identification of the hydrolytic enzymes involved in follicle rupture during vertebrate ovulation remains a central challenge for research in reproductive biology. Here, we report a previously uncharacterized approach to this problem by using an in vitro ovulation system in the medaka, Oryzias latipes, which is a small freshwater teleost," wrote K. Ogiwara and colleagues, Hokkaido University.

"We found that follicle rupture in the medaka ovary...


Source: Women's Health Weekly (2005-08-18)

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