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Women's Health Weekly

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Breast Cancer



Different diagnostic methods for breast cancer compared



August 25th, 2005

Different diagnostic methods for breast cancer were compared.

"Determination of Her-2/neu overexpression in breast cancer has previously been shown to be of prognostic significance. In this study, Her-2/neu expression in breast cancer was characterized by real-time PCR (RLT-PCR) based LightCycler-HER-2/neu DNA quantification with immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). Fifteen specimens of invasive breast cancer (whole tissue sections as well as micro-dissected tumor cells) were subjected to RLT-PCR," researchers in Germany reported.

"Additionally, IHC and FISH were performed. Her-2/neu overexpression was detected by...


Source: Women's Health Weekly (2005-08-25)

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